Aciphex FAQ
What is Rabeprazole (Aciphex) is used for:
Aciphex is used to treat duodenal ulcers, gastroesophageal reflux disease (GERD), erosive or ulcerative GERD. It's also used in a condition where pancreatic tumors cause over-production of gastric acid (Zollinger-Ellison Syndrome). Aciphex may be used with some types of antibiotics to treat certain types of ulcers. If needed Aciphex can be used to treat other conditions as determined by your doctor.
Aciphex (Rabeprazole) is a proton pump inhibitor (PPI). It is a medicine that reduce gastric acid secretion by blocking the final step of acid production by the stomach lining.
What is the brand and the generic name for this drug?
Aciphex - brand; Rabeprazole - generic name
Do NOT use Aciphex (Rabeprazole) if:
- you are allergic to any ingredient in Aciphex
- Contact your doctor or health care provider right away if any of these apply to you.
Before using Aciphex (Rabeprazole):
Some medical conditions may interact with Aciphex. You should tell your doctor or pharmacist if you have any medical conditions or problems, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, dietary supplement, or herbal preparation
- if you have allergies to medicines, foods, or other substances
- if you have severe liver problems
There are Some MEDICINES That MAY INTERACT with Aciphex (Rabeprazole). Tell your doctor if you are taking any other medicines, especially any of the following:
- Imidazoles (eg, ketoconazole, voriconazole) because some actions and side effects of Aciphex (Rabeprazole) may be increased
- HIV protease inhibitors (eg, ritonavir) or imidazoles (eg, ketoconazole) because the effectiveness of these medicines may be decreased
- Warfarin because side effects, such as bleeding may be increased by Aciphex (Rabeprazole)
- This is not a complete list of all interactions that may occur. Ask your doctor or health care provider if Aciphex may interact with some other medicines that you are taking. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Aciphex:
Use Rabeprazole (Aciphex) as directed by your doctor. For exact dosing instructions, please check the label on the medicine.
Aciphex (Rabeprazole) may be taken with or without food.
- Swallow the whole tablets. Do not break, chew, crush, or split the tablets. If you have difficulty or you can't swallow the tablets, consult your doctor or pharmacist for other suggestions on how to take the medicine.
- You should not take Rabeprazole within 2 hours of an imidazole (eg, ketoconazole). This will help minimize the drug interaction between these 2 medicines.
- If you miss a dose of Aciphex and you're taking one dose every day, take the missed dose in the same day if you remember. If you do not remember until the next day, skip the missed dose and go back to your regular dosing schedule. Don't think to take 2 doses at once, because is wrong.
You have to ask your doctor any questions you may have about how to use Aciphex (Rabeprazole).
Important safety information about Aciphex:
- It is possible to Aciphex to cause increasing sensitivity to the sun. You should avoid exposure to the sun, sun lamps, or tanning booths until you know your reactions to Rabeprazole. You may use a sunscreen or protective clothing if you have to go out for a longer period of time.
- LAB TESTS may be performed to monitor your progress or check for side effects. Be sure you keep all appointments to doctor and labs.
- If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Rabeprazole during pregnancy. It is unknown if Aciphex (Rabeprazole) is excreted in breast milk. Do not breast-feed while taking Aciphex.
Possible side effects of Aciphex (Rabeprazole):
- All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
- Headache.
- Seek medical attention right away if any of these SEVERE side effects occur:
- Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).
What is the shelf life of the pills?
- The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.


